Crown
scientific
Cellular Therapies and Biologics - Research and ConsultingOver a decade of experience in regenerative medicine, immunotherapies, MSC therapies, exosomes, secretome, and tissue therapies.
Cell Therapies
Mesenchymal Stem Cells
Mesenchymal stem cells (MSCs) modulate the immune system to promote tissue repair and decrease inflammation. They can differentiate into various cell types and release healing molecules. MSCs are found in almost all human tissues, making them widely accessible for regenerative medicine. They are also immunoprivileged, allowing their use in allogeneic (donor-derived) therapies without significant side effects. MSCs are being studied for their potential in treating various medical conditions, promising a new era in personalized medicine and therapeutic interventions.
Biologics
Secretome
The secretome is a complex mixture ("soup") of molecules like proteins, peptides, cytokines, and exosomes secreted by cells, essential for communication and biological processes. Its composition and function vary based on the cell type and specific processing techniques.
In regenerative medicine, the secretome is studied for its potential to replicate stem cell therapy benefits, providing a scalable and safer alternative for treatments like wound healing and organ regeneration. Research into the secretome is expanding its clinical applications and enhancing our understanding of cellular communication and disease mechanisms.
Tissue Products
Perinatal Tissues
Perinatal tissues, which are abundant in stem cells and growth factors, have been utilized for centuries to heal wounds and protect blood vessels. Traditionally applied topically, these tissues promote healing and prevent infection. Modern science has validated and expanded their use by processing them into various forms, such as grafts and injectables, for a wide range of medical applications, including treating chronic wounds, aiding in surgical recovery, and facilitating organ regeneration. This ancient practice has evolved into a sophisticated, scientifically backed branch of regenerative medicine.